Description of RPA
نویسنده
چکیده
RPA (Robust Probabilistic Averaging) package provides tools for analyzing probe reliability and differential gene expression on Affymetrix short oligonucleotide arrays. RPA provides explicit estimates probe reliability, and a probeset-level estimate of differential gene expression between a user-specified reference array and the other arrays. Probabilistic formulation allows incorporation of prior information concerning probe reliability into gene expression analysis within a principled framework. The underlying probabilistic model for probe-level observations is described in Lahti et al..
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